Indo-US School on Biological Timekeeping

5-15 July 2021 (plans on hold due to COVID second wave in India, stay tuned for more updates)

JNCASR, Jakkur, Bengaluru - 560064

Karnataka, India

Sponsored by

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Faculty

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Amita Sehgal

PhD

John Herr Musser Professor of Neuroscience, Perelman school of medicine, UPenn, USA

Her work focuses on understanding the molecular and cellular networks that drive behavior, in particular, rhythmic behaviors such as sleep using the fruit fly, Drosophila melanogaster and mice. Her research has provided insight into mechanisms of the circadian clock, how clocks synchronize to light and how clocks interact with body systems to drive rhythms of behavior and physiology. They have also identified genes and circuits that underlie the homeostatic drive for sleep. Altogether, her work provides an understanding of how internal clocks drive body rhythms, how and why a sleep state occurs, and the extent to which clocks and sleep impact general physiology and aging.

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William Schwartz

MD

Professor, Department of NeurologyAssociate Chair of Research & Education, Department of Neurology, The University of Texas at Austin, USA

His work primarily focuses on the suprachiasmatic nucleus (SCN) of the hypothalamus which is the circadian pacemaker in mammals. It also includes functional localization and energy metabolism, light-induced and endogenous gene expression, and the underyling dual oscillatory structure of the circadian pacemaker. His work is concentrated at the tissue, organismal, and even supra-organismal levels of analysis, and how all levels of biological organization contribute to the emergent properties and increased complexity of the circadian system as a whole.

Timeline for application

18 Feb

Application opens.

Applications are now open!

30 apr

Deadline for applications

Screening of applications and selection of participants begins.

25 may

Announcement of selected candidates

Names of 25 selected candidates will be announced.

ON HOLD due to COVID second wave in India.

12 jun

Deadline for registration and fee payment

Selected participants must register with 4500 INR fee to help cover the cost of food and accommodation.

15 jun

Announcement of waitlisted candidates (if any)

Waitlisted candidates will be notified by 15th June. Such candidates must pay registration fee and register before 20th June.

Eligibility and application
PhD Students
Who are engaged in or plan to pursue biological rhythms research

Master's students

With a demonstrated interest in biological rhythms

Undergraduate students

Exceptionally motivated students with a demonstrated interest in biological rhythms research

All applicants must fill out a clear statement of purpose indicating their motivation to participate in this school. Selected participants will be required to pay a registration fee* of INR 4500. Participants from India will be provided 3-tier AC train fare and local hospitality. Selected participants will be automatically registered for a 2-day International Conference on Chronobiology held between 16 - 17 July at JNCASR.
* A small fraction of registered participants may be offered a waiver of the fee on a case-to-case basis, following a review of their application forms.
Apply to the school by clicking here

Topics to be covered

Orientation Topics

Instructors:

William Schwartz

Sheeba Vasu

Anuranjan Anand

Nishikant K Subhedar

Mewa Singh

● Introduction to biological rhythms
● Adaptive significance of rhythms
● Introductory genetics and its connection to behaviour
● Introductory vertebrate neuroscience
● Historical perspective of the field of chronobiology

● Statistical analysis of data

Circadian Rhythms

Instructors:

William Schwartz

Sheeba Vasu

Amita Sehgal

Katja Lamia

Joanna C. Chiu

Patrick Emery

Brian Zoltowski

Mammalian Clocks:
● Suprachiasmatic nucleus: Master circadian pacemaker in mammals
● Mammalian clock circuits
● Mammalian molecular clockwork, metabolism
● Human circadian disorders
Fly Clocks:
● Insect Clocks – cellular and molecular mechanisms
● Input pathways and mechanisms of entrainment of circadian clocks
● Circadian pacemaker neuronal circuits in insects
● Sleep and metabolism
Molecular mechanisms of non-canonical clocks
Chemical modulators of clock function

Seasonal Rhythms

Instructors:

Vinod Kumar

Joanna C. Chiu

Sangeeta Rani

● Concept of seasonality
● Non-photic time cues for seasonal clocks
● Neuroendocrine regulation of seasonal clocks
● Photoperiodism in insects

Modelling and Analysis

Instructors:

Sriram K

Abhilash Lakshman

Sheeba Vasu lab

● Modeling circadian molecular clocks and circuits
● Timeseries analysis of rhythms - concepts and methods